Job Description
Join BioGenix Therapeutics, a leader in innovative drug development, as we pioneer next-generation therapeutics for rare diseases. Our Cambridge-based R&D hub is seeking a Senior Pharmaceutical Research Scientist to drive breakthrough discoveries in molecular biology and translational medicine. You'll collaborate with cross-functional teams to advance preclinical candidates through IND-enabling studies, contributing directly to therapies that transform patient lives. We offer competitive compensation, comprehensive benefits, and a culture that celebrates scientific excellence and innovation.
Responsibilities
- Lead design and execution of complex in vitro and in vivo experiments to validate drug targets and mechanisms
- Develop and optimize analytical methodologies (HPLC, LC-MS, NMR) for compound characterization and stability testing
- Prepare regulatory documentation (CTDs sections) and ensure compliance with FDA/EMA guidelines
- Mentor junior scientists and oversee laboratory operations including SOP development and GMP compliance
- Present research findings at international conferences and publish in high-impact journals
- Collaborate with CMC teams to scale up synthesis processes for preclinical studies
- Monitor competitive landscape and emerging technologies to identify strategic research opportunities
Qualifications
- PhD in Pharmaceutical Sciences, Medicinal Chemistry, or related field with 5+ years industry experience
- Expertise in drug discovery workflows from target identification to IND submission
- Proficiency in molecular biology techniques (CRISPR, qPCR, Western blot) and cell-based assays
- Demonstrated success in leading multi-disciplinary projects with cross-functional teams
- Strong publication record in peer-reviewed journals and conference presentations
- Experience with regulatory affairs (FDA/EMA) and GLP/GMP environments
- Excellent problem-solving skills with ability to troubleshoot complex experimental challenges
- Validated track record of advancing compounds through preclinical development stages