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Principal R&D Scientist - Gene Therapeutics

Helix Quantum Therapeutics
Boston
Salary Estimate
USD 165.000 – USD 210.000
Latest
Live Update
21 Mei 2026
Deadline
21 Mei 2027

Job Description

Are you ready to redefine the boundaries of modern medicine? Helix Quantum Therapeutics is seeking a visionary Principal R&D Scientist to lead our translational gene-editing division in Boston, MA. In this high-impact role, you will champion the discovery and design of next-generation therapeutic platforms, bridging the gap between molecular innovation and clinical validation.

We offer a state-of-the-art laboratory environment, a culture of intellectual curiosity, and a highly competitive compensation package. If you are a driven researcher with a passion for transforming lives through scientific breakthroughs, we invite you to join our world-class team.

Responsibilities

  • Lead the strategic design and execution of novel gene-editing R&D pipelines targeting rare genetic disorders.
  • Collaborate closely with cross-functional computational biology, bioinformatics, and pharmacology teams to accelerate platform discovery.
  • Translate early-stage, proof-of-concept biological assays into scalable and robust therapeutic delivery candidates.
  • Author and review high-impact scientific publications, intellectual property/patent filings, and regulatory IND documentation.
  • Mentor and guide a talented team of junior R&D scientists, research associates, and laboratory technicians.
  • Evaluate emerging global technologies, platforms, and external research partnerships to maintain the company’s competitive scientific edge.

Qualifications

  • Ph.D. in Molecular Biology, Bioengineering, Biochemistry, or a highly related life sciences discipline.
  • Minimum of 5+ years of post-PhD industry experience within a biotech, pharmaceutical, or advanced research institution.
  • Proven track record of developing cell-based assays, gene therapy vectors, or cellular therapeutics.
  • Deep hands-on expertise with advanced CRISPR systems, next-generation sequencing (NGS), and molecular cloning methodologies.
  • Strong analytical and quantitative mindset, with familiarity in statistical tools or computational languages (e.g., Python or R).
  • Excellent communication and leadership capabilities, evidenced by a strong portfolio of peer-reviewed publications.

Required Skills

Biotechnology CRISPR Gene Editing Molecular Biology Assay Development R&D NGS Python Biochemistry Intellectual Property

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